Zinc and Diseases of the Digestive Tract / Edition 1

by J.D. Kruse-Jarres, J. Schïlmerich

Overview

Zinc has an important role in human physiology due to its involvement in numerous enzymatic reactions and its other functions as part of hormones and structural proteins. As a consequence a wide variety of symptoms may occur in different states of zinc deficiency. Several diseases of the digestive tract can lead to zinc deficiency and consequently to deficiency symptoms.
This book, the proceedings of an International Falk Workshop held in Freiburg, Germany, on 27 October 1996, aims at a dialogue between basic researchers and gastroenterologists in order to improve the understanding of the role of zinc in disorders of the digestive tract. Based on lectures on the role of zinc in cell biology, the pathophysiology of zinc deficiency and consequently the possibilities of zinc substitution in these disorders is discussed. It is hoped that this book will initiate fruitful discussions and collaborations leading to a better knowledge of the role of this trace element in gastroenterology.

Product Details

ISBN-13:	9780792387244
Publisher:	Springer Netherlands
Publication date:	06/30/1997
Series:	Falk Symposium , #94
Edition description:	1997
Pages:	128
Product dimensions:	6.10(w) x 9.25(h) x 0.01(d)

About the Author

Kruse-Jarres, J.D. (Katharinenhospital Stuttgart); Scholmerich, J. (Universitat Regensburg)

Table of Contents

Preface. Section I: Metabolism and Functions of Zinc. 1. Basic principles of zinc metabolism; J.D. Kruse-Jarres. 2. Intestinal absorption of zinc; B. Lönnderdal. 3. Zinc deficiency; P.J. Aggett. 4. Zinc, the immune and endocrine system, and aging; N. Fabris. Section II: Experimental and Clinical Data. 5. The role of zinc in hepatic encephalopathy; O. Riggio, P. Fiore. 6. Experimental effects of zinc in liver and gut; A. Parés, et al. 7. Zinc and immune function in Crohn's disease; R.P.H. Thompson. 8. Zinc, cytokines and liver disease; C.J. McClain, et al. Section III: Clinical Findings and Therapeutic Effects. 9. Zinc and the stomach; anti-ulcer activity of zinc compounds; K.D. Rainsford. 10. Zinc in the treatment of diarrhea and chronic intestinal disorders; C. Folwaczny. 11. Zinc treatment in chronic liver diseases; K. Grüngreiff, D. Reinhold. 12. Zinc in the treatment of Wilson's disease; P. Ferenci. Index.

Editorial Reviews

Reviewer: Michael D. Brown, MD (Rush University Medical Center)
Description: This book contains the proceedings of an international workshop on zinc, covering the metabolism, gut physiology, and clinical applications of zinc in the treatment of both gastrointestinal and liver diseases.
Purpose: It aims to enhance the understanding of zinc and its role in gastrointestinal diseases among investigators and clinicians in the field of gastroenterology. This text provides comprehensive information on zinc and the GI tract that would be difficult to find in any other text or journal.
Audience: It is written for both basic science investigators and clinical gastroenterologists. The latter would probably benefit most from reading this text, but may not be pulled in by the title, which strongly suggests a limited-interest basic science text. It provides some very interesting insights into gastrointestinal diseases that cannot be found elsewhere. The contributors are all invited experts who presented at the international workshop.
Features: The text covers zinc absorption and metabolism as well as the clinical findings and consequences of zinc deficiency. Specific illnesses such as diarrhea, immune dysfunction, aging, and ulcerogenesis are covered in relation to aberrations in zinc metabolism. Much of the clinical information concerns zinc and liver disorders such as Wilson's disease. The book is quite detailed in this area and provides many unique insights. The chapters on zinc and treatment of chronic liver diseases provide information that can be applied immediately in a clinical setting. It is surprisingly well illustrated with graphs, tables, and schematics. The references are very up to date and detailed. The index is adequate and the text is above average in appearance for a workshop monograph.
Assessment: This is a surprising publication that will hold the interest of any gastroenterologist or investigator in the area of nutrition or zinc metabolism. It excels at its aim of improving the knowledge base of the reader in the area of zinc physiology and this trace mineral's role in GI and liver diseases. No other recent text covers the material with this level of detail.

Doody's Review Service

4 Stars! from Doody

This book contains the proceedings of an international workshop on zinc, covering the metabolism, gut physiology, and clinical applications of zinc in the treatment of both gastrointestinal and liver diseases. It aims to enhance the understanding of zinc and its role in gastrointestinal diseases among investigators and clinicians in the field of gastroenterology. This text provides comprehensive information on zinc and the GI tract that would be difficult to find in any other text or journal. It is written for both basic science investigators and clinical gastroenterologists. The latter would probably benefit most from reading this text, but may not be pulled in by the title, which strongly suggests a limited-interest basic science text. It provides some very interesting insights into gastrointestinal diseases that cannot be found elsewhere. The contributors are all invited experts who presented at the international workshop. The text covers zinc absorption and metabolism as well as the clinical findings and consequences of zinc deficiency. Specific illnesses such as diarrhea, immune dysfunction, aging, and ulcerogenesis are covered in relation to aberrations in zinc metabolism. Much of the clinical information concerns zinc and liver disorders such as Wilson's disease. The book is quite detailed in this area and provides many unique insights. The chapters on zinc and treatment of chronic liver diseases provide information that can be applied immediately in a clinical setting. It is surprisingly well illustrated with graphs, tables, and schematics. The references are very up to date and detailed. The index is adequate and the text is above average in appearance for a workshopmonograph. This is a surprising publication that will hold the interest of any gastroenterologist or investigator in the area of nutrition or zinc metabolism. It excels at its aim of improving the knowledge base of the reader in the area of zinc physiology and this trace mineral's role in GI and liver diseases. No other recent text covers the material with this level of detail.

Michael D. Brown

Comprising the proceedings of the International Falk Workshop (Part IV of the Gastroenterology Symposia 1996) held in Freiburg-im-Breisgau, Germany in October 1996, this volume contains 1 2 contributions, divided into three sections: the metabolism and functions of zinc; experimental and clinical data; and clinical findings and therapeutic effects. The volume aims at a dialogue between basic researchers and gastroenterologists in order to improve the understanding of the role of zinc in disorders of the digestive tract. Based on lectures on the role of zinc in cell biology, the pathophysiology of zinc deficiency and consequently the possibilities of zinc substitution in these disorders are discussed in depth. Annotation c. by Book News, Inc., Portland, Or.

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